Neomycin: is an aminoglycoside bactericidal antibiotic that its antimicrobial action results from the fixation of the 30 subunit of ribosomes. Also disturbs the bacterial membrane permeability. Neomycin: active against gram (-)negative and gram (+)postive bacteria, such as Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Streptococ- cus faecails, Haemophilus influenzae, Mycobacterium tuberculosis , proteuse vulgaris ,Bacillus anthracis, Salmonella spp. And Shigella spp.
Broiler Chickens: waki-neomycin used for treatment of diarrhea associated with salmonellosis that caused by Salmonella spp.
waki-neomycin reduce mortalities associated with Colibacillosis caused by Escherichia coli and the diarrhea caused by any of the susceptible organisms that mentioned above.
Each 1 gm contains:………………………………………….Neomycin Sulphate 300 mg (Equivalent to Neomycin base 210 mg)
• DOSAGE & ROUTE OF ADMINISTRATION
Route of administration: Orally. For whole product:0.05 waki-neomycin/ kg body weight for 3-5 days. 0.5gm waki-neomycin/ liter of drinking water for 3-5 days
• CONTRA –INDICATION
• Do not administer to dehydrated animals with renal failure or with respiratory depression.
• Do not administer to birds with a history of hypersensitivity to the antibiotic.
• WITHDRAWAL PERIOD
Broiler Chickens: 5 days
• TARGET SPECIES
Stored at temperature not exceeding 30 C˚, in dry place, away from light, and to be used immediately after opening and Reconstituting
• Warning& Precaution
Administer in a good quantity of water to consume the dose completely.
Prepare the medicated water daily.
Do not administer with neuromuscular blockers, general anesthetics, anti diuretics or other aminoglycosides
The prolonged use can cause malabsorption syndrome & intestinal dysbacteriosis. At high dose and prolonged use can cause nephrotoxis and ototoxis effect. Neomycin is particularly toxic to the auditory and renal system. Aminoglycosides may impair neuromuscular transmissions if used peri-operatively in association with anesthesia.