Lincomycin is a lincosamide antibiotic produced by Streptomyces lincolensis. Lincomycin is bacteriostatic in action inhibiting the protein synthesis predominantly by binding to the 50Sribosomal subunits of bacteria. Depending on the sensitivity of micro-organisms, and on the concentration of the active substance the protein synthesis inhibition antibacterial action can either be bacteriostatic or bactericide. Lincomycin is active against a wide range of Gram-positive bacteria, such as staphylococci, streptococci, β-haemolytic streptococci, corynebacteria, Erysipelothrix spp., and anaerobic bacteria, such as clostridia, as well as Leptospira spp. and Mycoplasma spp.
Treatment of infection caused by mycoplasma and bacteria susceptible to lincomycin for example: Chicken: necrotic enteritis caused by Clostridium perfringens
Each one gram contains:………………lincomycin Hcl 468 mg
(eq. to lincomycin base 400 mg).
• DOSAGE & ROUTE OF ADMINISTRATION
orally via drinking water
• CONTRA –INDICATION
Do not administer to animals with known hypersensitivity to lincomycin. Do not use if resistance to lincosamides has been detected Do not administer to horses, ruminants, guinea pigs, hamsters, chinchilla and rabbits. Ingestion by these species may result in severe gastrointestinal effects.
• WITHDRAWAL PERIOD
Meat and offal of chicken : 7 days.
• TARGET SPECIES
– Calves and lambs .
– Chicken .
• FOR ACTIVE INGREDIENT
20 mg lincomycin per kg of body weight for 7 days.
200 mg lincomycin/ litre of drinking water .
Calves and lambs :
10 mg lincomycin / kg of body weight for 3-5 days.
Stored at temperature not exceed 30 C˚.