Lincomycin is a lincosamide antibiotic produced by Streptomyces lincolensis. Lincomycin is bacteriostatic in action inhibiting the protein synthesis predominantly by binding to the 50Sribosomal subunits of bacteria. Depending on the sensitivity of micro-organisms, and on the concentration of the active substance the protein synthesis inhibition antibacterial action can either be bacteriostatic or bactericide. Lincomycin is active against a wide range of Gram-positive bacteria, such as staphylococci, streptococci, β-haemolytic streptococci, corynebacteria, Erysipelothrix spp., and anaerobic bacteria, such as clostridia, as well as Leptospira spp. and Mycoplasma spp.
• Target species
Royalprol is concentrated solution contain twin anticoccidials that provides a synergistic effect which is highly effective in the control of major coccidiosis causing Eimeria species of birds. Amprolium hydrochloride acts upon the first generation schizont to prevent merozoites production and that acts as competitive inhibitor of thiamine in the parasite metabolism. It exhibits high activity against E. tenella and E. acervulina. Ethopabate has anticoccidial activity especially against E. maxima and E. brunetti; and the synergistic combination of amprolium hydrochloride and ethopabate is effective against E. necatrix.
For prophylaxis and treatment of coccidiosis in the broiler chicken
• Dosage& Route of administration
Route of administration: orally in drinking water. For whole product: For treatment of outbreaks: 1 ml of Royalprol/8.64 kg of body weight (one liter of Royalprol per 900 liter of drinking water), for 5-7 days.
Stored at temperature not exceed 30 C˚.
• Withdrawal time
Meat : nil
• Warning & Precaution
1. The medicated water should be usedas a sole source of drinking
2. The medicated water should be consumed within 24 hours.
• Contra –Indication
• Do not use in birds which are producing or may in future produce egg or egg product for human consumption
• Side – Effects
No side effects when used with the recommended doses.