Tilmicure 250 is a semi synthetic macrolide antibiotics, oral solution, containing Tilmicosin phosphate. Tilmicosin is a semi-synthetic antibiotic of the macrolide group and is believed to affect protein synthesis. It has bacteriostatic action but at high concentrations it may be bactericidal This antibacterial activity is predominantly against Gram-positive microorganism with activity against certain gram-negative ones and Mycoplasma of a bovine, porcine, ovine and avian origin. Cross-resistance between tilmicosin and other macrolides and lincomycin has been observed. In Poultry: As early as 6 hours after oral administration of 75 mg tilmicosin/l drinking water, the average active substance concentrations detected in lung and alveolar tissue were 0.63 μg/g and 0.30 μg/g respectively. 48 hours after the start of treatment, the tilmicosin concentrations in lung and alveolar tissue were 2.3 μg/g and 3.29 μg/g respectively.
– Chickens: For the treatment and prevention of respiratory disease in chicken flocks, associated with Mycoplasma gallisepticum and M. synoviae.
– Turkeys: For the treatment and prevention of respiratory disease in turkey flocks, associated with Mycoplasma gallisepticum , M. synoviae , M. meleagridis and M. Iowae .
Each 1ml contain:
Tilmicosin phosphate 278mg equivalent to Tilmicosin base 250mg.
• DOSAGE & ROUTE OF ADMINISTRATION
Chickens and Turkeys (except hens producing eggs for human consumption) To be included in the drinking
water at a daily dose of
Chickens: 15-20 mg/kg bodyweight for, 3-5 days.
Turkeys:10-27 mg/kg bodyweight for, 3-5 days.
which may achieved by the inclusion (30 ml Tilmicure per 100 litres). For 3-5 days.
• CONTRA –INDICATION
Not used in chicken producing eggs for human consumption
• WITHDRAWAL PERIOD
Meat : 12 days.
• SIDE EFFECTS
Non in recommended dose
Store dry, in a well closed packing, below 30 C and protected from light.
Keep out of reach of children.