Apracure: contains Apramycin which is a broad-spectrum aminocyclitol antibiotic produced by a strain of Streptomyces tenebrarius. Apracure is bactericidal at minimum inhibitory concentrations. Apracure is effective against both Gram-negative and Gram-positive bacteria and some strains of mycoplasma at concentrations of 16 ug/ml or less. It is effective against most field strains of Escherichia coli and salmonellae.
-Apracure is indicated for the treatment of bacterial enteritis associated with organisms susceptible to apramycin in chicken. -Escherichia coli septicaemia in young chickens.
Each 100 gm contains:
Apramycin sulphate ………86.5 gm
Eq.to (59.5 gm apramycin base)
• DOSAGE & ROUTE OF ADMINISTRATION
Route of administration: orally via drinking water
For active ingredient :
Chicken: 20-25 mg apramycin per kg of body weight, this is achieved by adding
50g apramycin activity per 100 to 200 liters of drinking water for 5 days.
Calves : 20_40mg apramycin / kg b.wt in drinking water for 5 days .
For whole product :
Chickens: 4.2 gm Apracure per 100 kg body weight, this is achieved by adding 50 gm Apracure per 100 liters of drinking water for 5 days.
Calves : 3.3 _ 6.7 gm apracure / 100 kg b.wt in drinking water for 5 days .
• CONTRA –INDICATION
Do not use in cases of known hypersensitivity to apramycin.
Do not use in cats.
• WITHDRAWAL PERIOD
Chickens: Meat: 7 days
Do not use in laying chickens when eggs are intended for human consumption.
• TARGET SPECIES
Apracure: is indicated for use in chickens.
• SIDE EFFECTS
No side effects when used with the recommended doses.
There was no mortality when chickens were given a single oral dose of 1000 mg/kg bodyweight. Chickens were given up to 5 times the
recommended level for 15 days with no untoward reaction
Stored at temperature not exceed 30 C˚.